AOD-9604

AOD‑9604 – Targeted Fat Metabolism Fragment

AOD‑9604 is a synthetic peptide fragment derived from the 177–191 amino acid sequence of human growth hormone (hGH), developed to study fat metabolism and adipose‑tissue signaling without the broad systemic effects of full‑length GH. In preclinical and clinical research, this fragment has been investigated for its ability to stimulate lipolysis (fat breakdown) and inhibit lipogenesis (fat formation) while leaving IGF‑1 and glucose regulation largely unaffected.

Key features

• Mechanism‑driven design: Mimics the fat‑modulating region of hGH (177–191), targeting adipose tissue rather than global growth hormone pathways.

• Dual metabolic action: Research suggests AOD‑9604 can promote lipolysis and reduce lipogenesis via beta‑3 adrenergic receptor activation and downstream hormone‑sensitive lipase signaling in fat cells.

• Metabolic and body‑composition focus: Studied in models of obesity and weight management for its effects on fat oxidation, adipose‑tissue activity, and body‑fat distribution.

• Non‑GH systemic profile: Trials and reviews report minimal impact on IGF‑1 levels or carbohydrate metabolism, distinguishing it from traditional GH‑based approaches.

  
  

Research applications

AOD‑9604 is used in research exploring:

• Adipose‑tissue metabolism, including fat release, oxidation, and inhibition of new fat storage.

• Obesity and metabolic‑disorder models evaluating weight change, body‑fat percentage, and regional fat accumulation.

• Potential secondary roles in cartilage, bone, and joint‑health research, based on preliminary findings in regenerative and musculoskeletal studies.

  
  

Recommended handling

• For controlled laboratory research use only, by qualified professionals.

• Store in a cool, dry environment protected from light; follow internal SOPs for peptide reconstitution, aliquoting, and disposal.

• Consult current literature when designing dosing protocols, model selection, and outcome measures.

  
  

Important disclaimer

All compounds sold by Rocky Peptide Chain, including AOD‑9604, are for research use only. They are not intended for human consumption, medical use, diagnostic purposes, or treatment of any disease or condition. No weight‑loss, cosmetic, or therapeutic claims are made or implied. Researchers are solely responsible for proper handling, study design, and compliance with all applicable regulations.