CJC 1295 with Dac

CJC‑1295 with DAC – Long‑Acting GHRH Analog

CJC‑1295 with DAC (Drug Affinity Complex) is a synthetic GHRH analog engineered to extend the duration of GH release by enhancing peptide stability and albumin binding. By activating pituitary GHRH receptors and remaining active in circulation for days, this long‑acting construct is widely used to investigate how sustained GH and IGF‑1 elevations influence growth, metabolism, body composition, and tissue repair in experimental models.

Key features

• Extended‑half‑life design: The DAC component enables covalent or high‑affinity binding to serum albumin, reducing renal clearance and extending CJC‑1295’s functional half‑life to roughly 6–8 days in humans in published studies.

• Robust GH/IGF‑1 stimulation: Research has shown dose‑dependent, multi‑day increases in plasma GH and IGF‑1 following a single subcutaneous administration, making it suitable for long‑window endocrine and anabolic studies.

• Endogenous secretagogue: Rather than providing exogenous GH, CJC‑1295 with DAC stimulates endogenous hormone release via GHRH receptor activation, allowing exploration of upstream pituitary regulation.

• Weekly‑style exposure: Because of its prolonged activity, CJC‑1295 with DAC is typically modeled in less‑frequent dosing paradigms (e.g., weekly or multi‑day intervals) compared with short‑acting GHRH analogs.

  
  

Research applications

CJC‑1295 with DAC is used in experimental systems examining:

• GH/IGF‑1 dynamics and endocrine signaling, including long‑term changes in baseline and pulsatile GH output and downstream anabolic markers.

• Body‑composition and metabolic models, where researchers track lean‑mass accrual, fat‑mass changes, nutrient partitioning, and resting energy expenditure under sustained GH exposure.

• Tissue repair, recovery, and cellular aging, including exploratory work on how prolonged GH signaling may impact muscle, cartilage, connective tissue, immune modulation, and neuroprotection.

  
  

Recommended handling

• For controlled laboratory research use only by qualified professionals.

• Store in a cool, dry environment away from light; follow institutional SOPs for peptide storage, reconstitution, aliquoting, and disposal.

• Consult current literature when designing dose, interval, and model selection to characterize both the magnitude and duration of GH/IGF‑1 responses.

  
  

Important disclaimer

All compounds sold by Rocky Peptide Chain, including CJC‑1295 with DAC, are for research use only. They are not intended for human consumption, medical use, diagnostic purposes, or treatment of any disease or condition. No claims are made or implied regarding muscle growth, fat loss, performance enhancement, or anti‑aging effects. Researchers are solely responsible for appropriate handling, experimental design, and compliance with all applicable regulations.